There are reports of cardiac arrhythmias and/or cardiac arrest following the rapid administration of large intravenous doses of SOLU-MEDROL (greater than gram administered over a period of less than 10 minutes). Bradycardia has been reported during or after the administration of large doses of methylprednisolone sodium succinate, and may be. 1 gram Vial —Each 16 mL (when mixed as directed) contains methylprednisolone sodium succinate equivalent to 1 gram methylprednisolone; If appropriate, administration of Solu-Medrol should be stopped, and the patient's condition should be treated accordingly. Alternative treatments, including the use of corticosteroid formulations that do. Methylprednisolone pharmacokinetics is linear, independent of route of administration. Distribution. Methylprednisolone is widely distributed into the tissues, crosses the blood-brain barrier, and is secreted in breast milk. The plasma protein binding of methylprednisolone in humans is approximately 77%. Metabolism.
Solumedrol 1 gram administration for communitySolu-Medrol is given to people with MS to shorten relapses. Learn what to expect , including side effects and tips, during your infusion treatment. Find patient medical information for Solu-Medrol Intravenous on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user. SOLU-MEDROL may be administered by intravenous or intramuscular injection and long-acting bronchodilators is 1–2 mg/kg/day in single or divided doses.]
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